Home » Intranasal vax reveals superior safety in animals: Biotech | India News

Intranasal vax reveals superior safety in animals: Biotech | India News

by newsking24

HYDERABAD: Even as Bharat Biotech has utilized to the Indian drug regulator for permission to conduct Phase-I/II trials of its intranasal Covid-19 candidate code named BBV154, the corporate stated the candidate has already proven superior safety towards SARS-CoV-2 in animal research.
BBV154 is a single-dose vaccine made utilizing novel chimpanzee adenovirus. “Mice and hamsters immunized with a single dose of ChAd-SARS-CoV-2-S conferred superior protection against SARS-CoV-2 challenge, more so than one or two intramuscular immunizations of the same vaccine and dose. Post-challenge with SARS-CoV-2, viral clearance was observed in both lower and upper airways,” the corporate stated on its web site.
The pre-clinical testing for toxicology, immunogenicity and problem research had been carried out in US and India. The outcomes of the examine have additionally been uploaded on biorxiv, a server that carries preprints of analysis work earlier than it’s peer reviewed.

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